The mouse promoter drives lens-specific expression of a tripple FLAG-tagged cDNA encoding amino acids 849 to 929 with a nuclear localization sequence. This amino acid section is predicted to act as a dominant negative. Lines AD5 (12 to 16 copies) and AD9 (12 to 19 copies) were generated. (J:165054)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count