The mouse promoter drives lens-specific expression of a tripple FLAG-tagged cDNA encoding amino acids 849 to 929 with a nuclear localization sequence. This amino acid section is predicted to act as a dominant negative. Lines AD5 (12 to 16 copies) and AD9 (12 to 19 copies) were generated. (J:165054)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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