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The CAG::KikGR transgene was designed with a CMV enhancer/chicken beta-actin promoter (CAGGS) promoter driving widespread expression of a Kikume Green-Red (KikGR) photoconvertible fluorescent protein (engineered from Favia favus), followed by a rabbit beta-globin polyadenylation site. Lines 33 and 75 were established. Mice from founder line 33 exhibit widespread expression of KikGR, while mice from founder line 75 exhibit widespread KikGR expression in a mosaic pattern allowing for analyzing cell morphology and determining cell behavior dynamics. (J:153627)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
