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A loxP site was inserted upstream of exon 2 and was followed by an FRT flanked neomycin and a second loxP site. A third loxP site was placed immedicately downstream of exon 2. Properly targeted mice were bred to mice expressing flp recombinase in order to remove the neomycin selection cassette and leave exon 2 surrounded by loxP sites. (J:165020)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
