Exon 2 was floxed and a FRT flanked neomycin cassette was inserted within intron 2 by homologous recombination. The selection cassette was removed by flpe mediated recombination. (J:164205)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count