A loxP site was inserted up stream of exon 2 and an FRT flanked neo/kan cassette and second loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo/kan cassette. (J:164582)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count