Tg(MMTV-LPAR2)6Gbm

The MMTV-lpa2 transgenic construct contains the 1.54 kb MMTV LTR and the full-length cDNA of FLAG-tagged human LPA2 receptor linked to the KCR fragment containing the exon II (E2), intron II (I2), exon III (E3), and polyadenylation signal (rbGpA) derived from rabbit beta-globin. Two MMTV-lpa2 (#LPA2-3 and #LPA2-6) founders passed the transgene through the germ line. (J:149661)