A loxP site and an FRT flanked neo-tk selection cassette were inserted in intron 7. A second loxP site was inserted in intron 8. The selection cassette was subsequently excised from properly targeted ES cells by transient flp recombinase expression. (J:163910)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count