LoxP sites were inserted surrounding exons 1-4 and a FRT flanked neomycin cassette was inserted between exon 4 and the 3' loxP site. The selection cassette was removed by flp-mediate recombination. (J:163700)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count