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A mouse bacterial artificial chromosome (BAC) containing the entire mouse Akrib7 gene, was modified by inserting the TagRFP-T reporter sequence. Express of the Red Fluorescent Protein (TagRFP-T variant) is under the direction of the mouse Akrib7, aldo-keto reductase family 1, member B7, promoter. Transgene expression is detected at high levels in the adrenal glands and endothelial cells of renal medullary arterioles of transgenic embryos aged E15.5. Renal vasculature associated expression is observed in Smooth Muscle Actin immunohistochemical positive cells that are closely associated with FLK1 and PECAM positive intrarenal arteries. Other possible sites of expression have not been characterized. (J:159099)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
