Exon 2 of the targeted gene was flanked by a loxP site in intron 1 and a FRT-flanked PGK-Neo sequence followed by a loxP site in intron 2. Flp mediated recombination removed the selection cassette leaving exon 2 floxed. (J:163812)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count