A floxed neo resistance cassette was inserted 5' to exon 1 as well as an additional loxP site within intron 1 by homologous recombination. The neo cassette was removed by cre mediated recombination. (J:163059)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count