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A fragment encoding cre recombinase fused to a modified estrogen receptor ligand-binding domain (ERT2) was cloned into a vector containing the human KRT18 promoter. The construct was injected into fertilized oocytes to generated transgenic mice. Two lines were obtained. Line 23 was used in the original reference. (J:163216)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
