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A 1.0 kb fragment encoding cre recombinase was placed between nucleotides -596 to +21 of the rat Fabp1 and nucleotides +3 to +2150 of the human growth hormone gene (hGH; GH1). The purified fragment and injected into FVB/N oocytes. RNase protection assays in 8-week old mice demonstrated cre mRNA expression levels in small intestine (high in proximal half, lower in distal portion) and cecum (moderate) with barely detectable levels in the colon. Expression was also detected in the liver. (J:65809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
