Homologous recombination duplicated the gene. Cre mediated recombination removed the floxed neo cassette leaving a portion of the gene floxed. Western blot analysis confirmed increased protein expression. (J:119643)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count