A1.8 kb rat osteocalcin promoter fragment was used to direct expression of a truncated human cDNA encoding only the extracellular and transmembrane regions of the type II TGF-beta receptor. Eight of nine founders expressed the transgene. The four lines showing the highest expression levels were characterized. (J:57333)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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