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The entire coding region of human TGFA was fused to the human SFTPC promoter and used for the transgene. Introns from the human growth factor gene were included to enhance transgene expression. The transgene is expressed in lung epithelial cells. Lines 2, 4, 28, and 6108 were generated with 3.1-, 2.3-, 4.3-, and 1.3-fold expression, respectively. (J:133163)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
