The tetracycline responsive element (TRE), minimal CMV promoter fused to the tetracycline operator, drives conditional expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of serine for proline at position 22 (P22S). Three lines were established (173.2, 173.3, and 176). (J:160704)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count