A hypomorphic allele Ppargtm1Auwwas crossed successively with transgenic C57Bl/6J mice expressing FLP and Cre recombinases to remove the frt flanked neomycin selection cassette and the loxP flanked exon B specific for the Pparg2 isoform. Absence of Pparg2 isoform specific transcripts was confirmed by RTPCR. (J:161746)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
10
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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