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The 5'UTR, exon 1, and exon 2 wwere replaced with a construct containing (5' to 3') an frt flanked neo cassette, tetracycline responsive (tetO/TRE) promoter, a myc-tagged Sod2 cDNA, and an IRES-EGFP. The absence of protein expression was confirmed by western blot analysis on embryonic fibroblast. (J:162190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
