The beta actin promoter is used to drive expression of either GFP or luciferase. The floxed GFP contains a polyadenylation sequence and is located upstream of the luciferase construct which also contains a polyadenylation sequence. Luciferase is not expressed until GFP is excised by cre. (J:86565)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count