A 3.36 kb fragment consisting of cre recombinase preceded by an internal ribosomal entry site (IRES) and followed by an FRT-neo-FRT cassette was inserted into the 3' UTR of exon 2 of Hoxb8. The neomycin cassette was subsequently removed by breeding with FLPe deleter animals. (J:162102)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count