The EGFP gene driven by the immunoglobulin heavy chain variable region (VH) and a floxed neo cassette were inserted 1.5 Kb upstream of the first non-coding exon. The VH-EGFP reporter gene is in the opposite orientation of Myc. This allele serves as a reporter of chromosomal T(12;15) translocation in B lymphocytes and plasma cells. (J:162138)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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