A mutant uncleavable form of the 26 kD protein was engineered by the deletion of the codons for the first to the twelfth amino acids of the wild type gene. This produces a membrane-associated protein that is bioactive. Under the control of the T cell specific human CD2 gene locus control region (LCR). (J:162144)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count