A floxed neo cassette with a 5' loxP site was inserted upstream of exon 4 and an additional loxP site was inserted downstream of exon 4. Cre mediated recombination removed the neo cassette leaving exon 4 floxed. (J:161294)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count