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The cDNA encoding cre recombinase was inserted downstream of the endogenous ATG codon in exon 2 of the Trh gene in a BAC containing the entire Trh gene and at least 30 kb and 40 kb of 5' and 3' flanking sequences respectively. The purified vector was used to generate transgenic lines. Two founder lines, 5 and 40, were subsequently analyzed. (J:162058)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
