This transgene consists of a mouse transthyretin (Ttr) minigene , which includes 3 kb of the Ttr promoter, the first and second exons of the Ttr gene, resistin (Retn) cDNA bearing the biologically active flag epitope at the 3' end and a polyA tail. Overexpression and quantification of Retn in white adipose tissue and liver was verified by northern blot, immunoblot (western) and radioimmunoassay. (J:91890)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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