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Cre mediated recombination removed exon 16 and the beta-geo cassette. The reduction in protein production was confirmed by western blot analysis on Setdb1tm2.1Enl/Setdb1tm2.2 embryonic stem cells transfected with a cre-ERT2 plasmid and treated with tamoxifen. (J:161089)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
