A loxP site was inserted upstream of exon 16 and a floxed beta-geo cassette was inserted downstream of exon 16. Cre mediated recombination removed the beta-geo cassette leaving exon 16 floxed. (J:161089)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count