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EN
DNA sequence encoding the human M1' segment was inserted immediately following the splice acceptor site of the mouse IgE M1 exon. In addition, an IRES element followed by a GFP construct modified to encode an F64A amino acid change and then a floxed neomycin selection cassette were all inserted downstream of the mouse IgE M2 exon. The selection cassette was subsequently excised by transient in vitro cre expression. (J:161452)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
