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This transgene consists of the chicken beta-actin promoter followed by a loxP flanked stop, a kinase-inactive Map3k7 with a K63W mutation, and a polyadenylation signal. Cre mediated recombination removes the stop and allows expression of the kinase-inactive Map3k7 gene. Map3k7 expression is increased about 4 fold and this is the highest expressing line. (J:117108)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
