A FRT-flanked Neo cassette and a single loxP site were placed 5' to exon 8 and a second loxP site was placed at the 3' the end of exon 8. The selection cassette and exon 8 were removed by flp and cre mediated recombination respectively. A shorter mRNA is produced consistent with the deletion of exon 8. (J:160811)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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