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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Rad51c
tm1.1Bcg
Alias:
Rad51C
*/neo
Rad51C
splice/neo
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Basic Information
Phenotypes
References Literature
Intron 5 was replaced with a neo cassette and a modified intron 5 in which a G to A nucleotide substitution 5 nucleotides into intron 5 altered the splice donor site of exon 5. Cre mediated recombination removed the neo cassette. (J:161642)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
4461202
129P2/OlaHsd
Targeted
Insertion, Nucleotide substitutions
--
1
9
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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