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A GFP construct modified to enhance function in mammalian systems was place under the control of a modified Pcp2 promoter. All ATG codons in exon 2 of Pcp2 and downstream of exon 2 have been deleted. The GFP construct contains about 100 mutations including a serine to threonine change at codon 65. Three founder lines were produced. Line 50 showed the highest levels of expression. (J:161694)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
