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EN
Exon 5 was replaced with an frt flanked neo cassette and a modified exon 5 in which nucleotide substitutions result in the amino acid substitutions of alanine for lysine at position 209 (K209A) and alanine for phenylalanine at position 213 (F213A). Flp mediated recombination removed the neo cassette leaving a single frt site downstream of the modified exon 5. The modified residues participate in T cell receptor contact. (J:160286)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
