A full-length Gli1 cDNA followed by sequence for a C-terminal 3X FLAG tag, an IRES, the Venus fluorescent reporter gene, an intron and poly(A) signal sequences were inserted into the locus downstream of a splice acceptor and loxP site flanked neomycin resistance gene cassette. Upon cre expression, the neo cassette is removed and FLAG tagged Gli1 gene and Venus gene expressed. (J:121411)
Basic Information
129 and C57BL/6 and CBA and Swiss Webster
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count