The transgene contains the tet operon (tetO) and a minimal CMV promoter controlling expression of a cDNA encoding rat cAMP-responsive element binding protein 1 (CREB1), alpha isoform; the coding sequence is followed by the SV40 intron and polyadenylation signal. (J:92225, J:92951, J:128618)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count