A loxP site was inserted upstream of the coding exon, and an frt and loxP flanked neo cassette was inserted downstream of the coding exon. Flp mediated recombination removed the neo cassette leaving the coding exon floxed. (J:161480)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count