A floxed neo cassette was inserted upstream of the coding exon and an additional loxP site was inserted downstream of the coding exon. Cre mediated recombination removes the neo cassette leaving the coding exon floxed. (J:160074)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count