Intron 6 was replaced with a lacZ cassette with a 5' loxP site and a 3' polyadenylation sequence, an frt flanked neo cassette, and a 3' loxP site. Flp mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:160285)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count