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LoxP sites were inserted to flank exon 3 of the Shoc2 (Sur-8) gene. The targeting vector also contained an frt-flanked neomycin resistance cassette. The vector was electroporated into W4 ES cells. Mutant mice were crossed to Actin-FLPe transgenic mice to remove the neo cassette, leaving the floxed allele. (J:161211)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
