The cDNA and a floxed neo cassette was inserted into the first coding exon. Cre mediated recombination removed the neo cassette. Immunohistochemistry confirmed increased Bcl2l1 protein expression in enteric ganglia of heterozygous mice. (J:159854)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count