Exons 2-4 were flanked by loxP sites and an FRT-flanked neomycin resistance cassette was placed in intron 1. Flp mediated recombination removed the neo cassette leaving exons 2 through 4 floxed. (J:161127)
Basic Information
(C57BL/6 x 129S1/SvImJ)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count