A loxP site was inserted upstream of exon 18 and a floxed neo cassette was inserted downstream of ezon 21. Cre mediated recombination removed the neo casette leaving exons 18 through 21 floxed. (J:161125)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count