A 3.0Kb region of the Crh promoter was PCR amplified from mouse bacterial artificial chromosome clone #129A14. The transgenic construct contains the 3.0Kb Crh promoter ligated to the cre coding sequence. The linearized construct was microinjected into pronuclei of FVB oocytes and a line was generated by crossing to C57BL/6. (J:162037)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
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Insertion
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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