A 3.0Kb region of the Crh promoter was PCR amplified from mouse bacterial artificial chromosome clone #129A14. The transgenic construct contains the 3.0Kb Crh promoter ligated to the cre coding sequence. The linearized construct was microinjected into pronuclei of FVB oocytes and a line was generated by crossing to C57BL/6. (J:162037)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count