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This allele contains exon 4 of the human TRP53 gene, with the human proline variant at codon 72 (dbSNP:rs1042522; 72P). Codon 270, in the unmodified exon 8 - corresponding to human TRP53 codon 273 - encodes arginine (270R; mouse wild-type). A single loxP site in intron 1 is retained from an excised loxP-flanked translational STOP and selection cassette. (J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
