A human beta Actin promoter was used to drive expression of a human BDNF cDNA. Two founders carried two copies at a single integration site. Both lines were very similar so only one was maintained. Expression dropped between 8 weeks and 9 months of age. (J:59465)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count