A construct containing tetracycline response elements with an antisense CMV promoter element and an frt flanked neo cassette was inserted into intron 1. In addition, exon 2 was flanked by loxP sites. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:160254)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count