A loxP site was inserted upstream of exon 3 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 8. Flp mediated recombination removed the neo cassette leaving exons 3 through 8 floxed. (J:160503)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count