The human BAC RP11-88L12 was modified to carry an in-frame P2A-Emerald GFP (EmGFP) insertion, a Zeocin cassette, and an SV40-Neo selection cassette. Expression is detected in early cardiac progenitors, embryonic heart tissues, and other tissues expressing NKX2-5 (e.g. foregut and branchial arches). Two lines were generated (lines 1 and 2). (J:160582)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
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Insertion
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--
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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